Full-width text (Ｌｉｋｅ ｔｈｉｓ) is emphasising that the original text is written using the Latin alphabet. Note that most abbreviations that are not in italics are written using the Latin alphabet as well. Italic text is Engrish (English written in katakana). Abbreviations in italics means that the Japanese version used some shorter form of an English word, but in katakana. Comic sans font is used to indicate an unusual way of writing a word (like writing English in hiragana or Japanese in katakana). In cases when I needed to emphasise that the word is Japanese (or when the text specifically commented about it being Japanese), I added the Japanese version as furigana.
Any feedback is appreciated.
Editing: Pryun, ZeHaffen